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Alomone Labs, LTD
S1PR5/EDG8 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 3
S1PR5/EDG8 (extracellular) Antibody (ASR-015-200UL) in WB
Western blot analysis of human THP-1 monocytic leukemia cell line lysate (lanes 1 and 4), human NK-92 natural killer cell line lysate (lanes 2 and 5) and human HL-60 promyelocytic leukemia cell line lysate (lanes 3 and 6) lysates: - 1-3. Anti-S1PR5/EDG8 (extracellular) Antibody (#ASR-015), (1:200).4-6. Anti-S1PR5/EDG8 (extracellular) Antibody , preincubated with the negative control antigen.
Product Details
ASR-015-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KLRGARYQPGAGLRAD, corresponding to amino acid residues 24-39 of mouse S1PR5 (EDG8), Extracellular, N-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; Lysophospholipid receptor B4; Nerve growth factor-regulated G-protein-coupled receptor 1; NRG-1; S1P receptor 5; S1P receptor Edg-8; S1P(5) receptor; S1P5; Sphingosine 1-phosphate receptor 5; Sphingosine 1-phosphate receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine-1-phosphate receptor LPB4
Gene Aliases: Edg-8; EDG8; Lpb4; Nrg1; S1P5; S1PR5; SPPR-1; SPPR-2
UniProt ID: (Human) Q9H228, (Rat) Q9JKM5, (Mouse) Q91X56
Entrez Gene ID: (Human) 53637, (Rat) 60399, (Mouse) 94226
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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