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Immunogen sequence: MAAVFDLDL ETEEGSEGEG EPELSPADAC PLAELRAAGL EPVGHYEEVE LTETSVNVGP ERIGPHCFEL LRVLGKGGYG KVFQVRKVQG TNLGKIYAMK VLRKAKIVRN AKDTAHTRAE RNILESVKHP FIVELAYAFQ TGGKLYLILE CLSGGELFTH LEREGIFLED TACFYLAEIT LALGHLHSQG IIYRDLKPEN IMLSSQGHIK LTDFGLCKES IHEGAVTHTF CGTIEYMAPE ILVRSGHNRA VDWWSLGALM YDMLTGSPPF TAENRKKTMD KIIRGKLALP PYLTPDARDL VKKFLKRNPS QRIGGGPGDA ADVQRH (1-325 aa encoded by B C000094)
RPS6KB2 (p70S6K beta) is a serine/threonine kinase with 2 non-identical kinase catalytic domains which phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
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Protein Aliases: 70 kDa ribosomal protein S6 kinase 2; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70-S6K 2; P70S6K2; Ribosomal protein S6 kinase beta-2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; S6 kinase 2; S6 kinase-related kinase; S6K-beta; S6K-beta-2; serine/threonine-protein kinase 14 beta; Serine/threonine-protein kinase 14B; SRK
Gene Aliases: 70kDa; KLS; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; RPS6KB2; S6K-beta2; S6K2; SRK; STK14B
UniProt ID: (Human) Q9UBS0, (Mouse) Q9Z1M4
Entrez Gene ID: (Human) 6199, (Rat) 361696, (Mouse) 58988
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