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Product Details
MA1-40180
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Horse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
Reu86.1
Immunogen
Human SAA.
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Protein G
Storage buffer
PBS with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1087177
Product Specific Information
MA1-40180 detects SAA from human and mouse samples.
MA1-40180 is raised against human SAA and Helix Pomatia Haemocyanine. It reacts specifically with SAA-1, the major isoform of SAA in plasma.
MA1-40180 has been successfully used in immunohistochemistry (frozen and paraffin), western blot, and immunoassay applications. It is recommended that users test the reagent and determine their own optimal dillutions.
The MA1-40180 immunogen is human SAA.
Target Information
The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: amyloid a; MGC111216; SAA; serum amyloid A 2; serum amyloid A protein; Serum amyloid A-1 protein; Serum amyloid A1 protein; Serum Amyloid-A; tumor protein p53 inducible protein 4
Gene Aliases: PIG4; SAA; Saa-1; SAA1; SAA2; TP53I4
UniProt ID: (Human) P0DJI8, (Mouse) P05366
Entrez Gene ID: (Human) 6288, (Mouse) 20208
activation of MAPK activity
receptor-mediated endocytosis
acute-phase response
positive regulation of cytosolic calcium ion concentration
platelet activation
neutrophil chemotaxis
cellular protein metabolic process
innate immune response
positive regulation of cell adhesion
macrophage chemotaxis
lymphocyte chemotaxis
regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of interleukin-1 secretion
negative regulation of inflammatory response
positive chemotaxis
cholesterol metabolic process
cell chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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