Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Immunogen sequence: ELKAKYYVQLE QLKKTVDDLQ AKLTLAKGEY KMALKNLEMI SDEIHERRRS SAMGPRGCGV GAEGSSTSVE DLPGSKPEPD AISVASEAFE DDSCSNFVSE
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 89%.
Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SH3 binding protein; SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK; SH3-domain binding protein 5 (BTK-associated); SH3BP-5
Gene Aliases: SAB; SH3BP-5; SH3BP5
UniProt ID: (Human) O60239
Entrez Gene ID: (Human) 9467
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