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          • Primary Antibodies ›
          • Sacsin Antibodies

          Proteintech

          SACS Polyclonal Antibody

          View all (3) Sacsin antibodies

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          Cite SACS Polyclonal Antibody

          • Antibody Testing Data (4)
          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 4

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          SACS Antibody (22265-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human gliomas tissue slide using 22265-1-AP (SACS antibody) at dilution of 1:100 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SACS Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          22265-1-AP

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.57 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kruppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ANKZF1 (ankyrin repeat and zinc finger domain containing 1), also known as ZNF744, is 726 amino acids in length and lacks a KRAB domain but contains one C2H2-type zinc finger and two ANK repeats. The gene encoding ANKZF1 localizes to chromosome 2.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: DKFZp686B15167; DnaJ homolog subfamily C member 29; protein phosphatase 1, regulatory subunit 138; Sacsin; sacsin molecular chaperone; spastic ataxia of Charlevoix-Saguenay (sacsin)

          View more View less

          Gene Aliases: A230052M14; ARSACS; DNAJC29; E130115J16Rik; KIAA0730; mKIAA0730; PPP1R138; RGD1305416; SACS; SPAX6

          View more View less

          UniProt ID: (Human) Q9NZJ4, (Mouse) Q9JLC8

          View more View less

          Entrez Gene ID: (Human) 26278, (Rat) 305940, (Mouse) 50720

          View more View less

          Function(s)
          Hsp70 protein binding chaperone binding proteasome binding low-density lipoprotein particle receptor binding
          Process(es)
          negative regulation of inclusion body assembly protein folding
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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