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Immunogen sequence: ATITYNVPEE KMEKGQPQPD NILSTASTGL INVAGAGTPA ISTNGLYSTV PHNVCEEKME NDQPQPNNVL STVQPVIIYL TATGIPGMNT RDQYATITHN VCEERVVNNQ PLPSNALSTV LPGLAYLATA DMPAMSTRDQ H
Highest antigen sequence identity to the following orthologs: Mouse - 22%, Rat - 23%.
This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cancer/testis antigen 14; CT14; putative tumor antigen; Sarcoma antigen 1
Gene Aliases: CT14; SAGE; SAGE1
UniProt ID: (Human) Q9NXZ1
Entrez Gene ID: (Human) 55511
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