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Invitrogen
SAMSN1 Polyclonal Antibody
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Product Details
PA5-100326
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SAMSN1(Accession Q9NSI8), corresponding to amino acid residues S123-D173.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849840
Product Specific Information
Antibody detects endogenous levels of total SAMSN1.
Target Information
SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hematopoietic adapter-containing SH3 and sterile alpha-motif (SAM) domains 1; hematopoietic adapter-containing SH3 and sterile α-motif (SAM) domains 1; Hematopoietic adaptor containing SH3 and SAM domains 1; Nash1; nuclear localization signals, SAM and SH3 domain containing 1; SAM and SH3 domain containing 2; SAM domain, SH3 domain and nuclear localisation signals, 1; SAM domain, SH3 domain and nuclear localization signals protein 1; SAM domain-containing protein SAMSN-1; SAMSN; SAMSN-1; SH3 protein expressed in lymphocytes 2; SH3-lymphocyte protein 2; SH3-SAM adaptor protein; SLy2; Src homology domain 3 (SH3)-containing adapter protein SH3 lymphocyte protein 2
Gene Aliases: 4930571B16Rik; 930571B16Rik; HACS1; Nash; NASH1; SAMSN1; SASH2; SH3D6B; SLy2
UniProt ID: (Human) Q9NSI8, (Mouse) P57725
Entrez Gene ID: (Human) 64092, (Mouse) 67742, (Rat) 170637
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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