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Invitrogen
SAR1B Polyclonal Antibody
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Product Details
PA5-18756
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (DHERLLESKEELD) corresponding to the internal amino acids of SAR1B (aa 104-116).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10985146
Product Specific Information
This antibody is predicted to react with human based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Target Information
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310075M17Rik; GTBPB; GTP-binding protein B; GTP-binding protein SAR1b; GTP-binding protein Sara; SAR1 gene homolog B; SAR1 homolog B; SAR1a gene homolog 2; SAR1b gene homolog; secretion associated, Ras related GTPase 1B; Secretion-associated Ras-related GTPase 1B; Small COPII coat GTPase SAR1B
Gene Aliases: 2310075M17Rik; 2900019I22Rik; ANDD; CMRD; GTBPB; SAR1B; SARA1B; SARA2; SARB
UniProt ID: (Human) Q9Y6B6, (Rat) Q5HZY2, (Mouse) Q9CQC9
Entrez Gene ID: (Human) 51128, (Rat) 287276, (Mouse) 66397
intracellular protein transport
biological_process
vesicle-mediated transport
antigen processing and presentation of peptide antigen via MHC class I
ER to Golgi vesicle-mediated transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
COPII vesicle coating
transport
protein transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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