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Invitrogen
SARS-CoV-2 3CLpro Polyclonal Antibody
FIGURE: 1 / 4
SARS-CoV-2 3CLpro Antibody (PA5-116940) in ICC/IF
Immunofluorescence analysis of SARS-CoV-2 3CLpro in 293T cells transfected with SARS-CoV-2 3CLpro fusion protein (top left) and untreated 293T cells (top right). Samples were incubated with SARS-CoV-2 3CLpro Polyclonal antibody (Product # PA5-116940) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Product Details
PA5-116940
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-306 of coronavirus 3CLpro (YP_0097252951)
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901570
Product Specific Information
Positive Samples: 293T
Immunogen sequence: MESLVPGFNE KTHVQLSLPV LQVRDVLVRG FGDSVEEVLS EARQHLKDGT CGLVEVEKGV LPQLEQPYVF IKRSDARTAP HGHVMVELVA ELEGIQYGRS GETLGVLVPH VGEIPVAYRK VLLRKNGNKG AGGHSYGADL KSFDLGDELG TDPYEDFQEN WNTKHSSGVT RELMRELNGG AYTRYVDNNF CGPDGYPLEC IKDLLARAGK ASCTLSEQLD FIDTKRGVYC CREHEHEIAW YTERSEKSYE LQTPFEIKLA KKFDTFNGEC PNFVFPLNSI IKTIQPRVEK KKLDGFMGRI RSVYPV
Target Information
Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has been attributed to a novel coronavirus (SARS-CoV). The SARS 3C-like protease (SARS 3CL (pro)) is a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for corona virus replication and is considered an attractive target for therapeutics against SARS.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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