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Invitrogen
SARS-CoV-2 Membrane Recombinant Rabbit Monoclonal Antibody (HL1088)
FIGURE: 1 / 2
SARS-CoV-2 Membrane Antibody (MA5-46924) in ICC/IF
Immunofluorescent analysis of SARS-CoV-2 Membrane in 293T cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SARS-CoV-2 (COVID-19) Membrane stained by SARS-CoV-2 (COVID-19) Membrane monoclonal antibody (Product # MA5-46924) diluted at 1:2,000. Blue: Fluoroshield with DAPI.
Product Details
MA5-46924
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1088
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) Membrane. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2937996
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
The coronavirus membrane protein (M) is the most abundant viral structural protein and plays a central role in virus assembly and morphogenesis|M protein forms a mushroom-shaped dimer, composed of two transmembrane domain-swapped three-helix bundles and two intravirion domains|M protein further assembles into higher-order oligomers|A highly conserved hinge region is key for conformational changes|The M protein dimer is unexpectedly similar to SARS-CoV-2 ORF3a, a viral ion channel|The interaction analyses of M protein with nucleocapsid protein (N) and RNA suggest that the M protein mediates the concerted recruitment of these components through the positively charged intravirion domain [PMID: 35931673]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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