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Proteintech
SART3 Polyclonal Antibody
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Product Details
18025-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SART3 Fusion Protein Ag12590 (1-357 aa encoded by BC093784)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATAAETSA SEPEAESKAG PKADGEEDEV KAARTRRKVL SRAVAAATYK TMGPAWDQQE EGVSESDGDE YAMASSAESS PGEYEWEYDE EEEKNQLEIE RLEEQLSINV YDYNCHVDLI RLLRLEGELT KVRMARQKMS EIFPLTEELW LEWLHDEISM AQDGLDREHV YDLFEKAVKD YICPNIWLEY GQYSVGGIGQ KGGLEKVRSV FERALSSVGL HMTKGLALWE AYREFESAIV EAARLEKVHS LFRRQLAIPL YDMEATFAEY EEWSEDPIPE SVIQNYNKAL QQLEKYKPYE EALLQAEAPR LAEYQAYIDF EMKIGDPARI QLIFERALVE NCLVPDLWIR YSQYLDRQ (1-357 aa encoded by BC093784)
Target Information
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HIV-1 Tat-interacting protein of 110kDa; hSART-3; MGC138188; mSART-3; p110 nuclear RNA-binding protein; SART-3; squamous cell carcinoma antigen recognized by T cells 3; Squamous cell carcinoma antigen recognized by T-cells 3; Tat-interacting protein of 110 kDa; Tip110; Tumor-rejection antigen SART3
Gene Aliases: AU045857; DSAP1; KIAA0156; mKIAA0156; P100; p110; p110(nrb); RP11-13G14; SART3; TIP110
UniProt ID: (Human) Q15020, (Mouse) Q9JLI8
Entrez Gene ID: (Human) 9733, (Mouse) 53890, (Rat) 304582
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
spliceosomal snRNP assembly
mRNA splicing, via spliceosome
cell morphogenesis
nucleosome assembly
regulation of gene expression
homeostasis of number of cells
hematopoietic stem cell proliferation
positive regulation of histone deubiquitination
RNA processing
mRNA processing
RNA splicing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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