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FIGURE: 1 / 1
SASH1 Antibody (PA5-90318) in WB
Western blot analysis of SASH1 in extracts of various cell lines. Samples were incubated with SASH1 Polyclonal antibody (Product # PA5-90318) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-90318
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SASH1 (NP_0560933)
Conjugate
Form
Liquid
Concentration
1.63 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806024
Product Specific Information
Immunogen sequence: MEDAGAAGPG PEPEPEPEPE PEPAPEPEPE PKPGAGTSEA FSRLWTDVMG ILDGSLGNID DLAQQYADYY NTCFSDVCER MEELRKRRVS QDLEVEKPDA SPTSLQLRSQ IEESLGFCSA VSTPEVERKN PLHKSNSEDS SVGKGDWKKK NKYFWQNFRK NQKGIMRQTS KGEDVGYVAS EITMSDEERI QLMMMVKEKM ITIEEALARL KEYEAQHRQS AALDPADWPD GSYPTFDGSS NCNSREQSDD ETEESVKFKR LHKLVNSTRR VRKKLIRVEE MKKPSTEGGE EHVFENSPVL; Positive Samples: U-87MG, Mouse lung
Target Information
May have a role in a signaling pathway. Could act as a tumor suppressor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2500002E12Rik; Proline-glutamate repeat-containing protein; putative adapter and scaffold protein 1; SAM and SH3 domain-containing protein 1
Gene Aliases: 1100001C18Rik; 2500002E12Rik; A330076K04Rik; dJ323M4; dJ323M4.1; KIAA0790; mKIAA0790; PEPE1; SASH1; SH3D6A
UniProt ID: (Human) O94885, (Mouse) P59808
Entrez Gene ID: (Human) 23328, (Mouse) 70097
protein polyubiquitination
positive regulation of endothelial cell migration
positive regulation of lipopolysaccharide-mediated signaling pathway
positive regulation of JUN kinase activity
positive regulation of angiogenesis
regulation of protein K63-linked ubiquitination
positive regulation of p38MAPK cascade
positive regulation of NIK/NF-kappaB signaling
regulation of protein autoubiquitination
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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