Proteintech

SC65 Polyclonal Antibody

FIGURE: 1 / 3

SC65 Antibody (15288-1-AP) in WB

Human bladder tissue were subjected to SDS PAGE followed by western blot with 15288-1-AP (SC65 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

SC65 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15288-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

Assay-dependent

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

SC65 Fusion Protein Ag7480 (92-437 aa encoded by BC001047)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.46 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DGGRADEWA CELRLFGRVL ERAACLRRCK RTLPAFQVPY PPRQLLRDFQ SRLPYQYLHY ALFKANRLEK AVAAAYTFLQ RNPKHELTAK YLNYYQGMLD VADESLTDLE AQPYEAVFLR AVKLYNSGDF RSSTEDMERA LSEYLAVFAR CLAGCEGAHE QVDFKDFYPA IADLFAESLQ CKVDCEANLT PNVGGYFVDK FVATMYHYLQ FAYYKLNDVR QAARSAASYM LFDPKDSVMQ QNLVYYRFHR ARWGLEEEDF QPREEAMLYH NQTAELRELL EFTHMYLQSD DEMELEETEP PLEPEDALSD AEFEGEGDYE EGMYADWWQE PDAKGDEAEA EPEPELA (92-437 aa encoded by BC001047)

Target Information

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transcriptome analysis of a dog model of congestive heart failure shows that collagen-related 2-oxoglutarate-dependent dioxygenases contribute to heart failure.

Scientific reports

Isono T,Matsumoto T,Suzaki M,Kubota S,Kageyama S,Kawauchi A,Wada A

Thu Dec 29 00:00:00 UTC 2022

P3H4 Promotes Malignant Progression of Lung Adenocarcinoma via Interaction with EGFR.

Cancers

Fang C,Liang Y,Huang Y,Jiang D,Li J,Ma H,Guo L,Jiang W,Feng Y

Fri Jul 01 00:00:00 UTC 2022

Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer.

Aging

Hao L,Pang K,Pang H,Zhang J,Zhang Z,He H,Zhou R,Shi Z,Han C

Tue Feb 04 00:00:00 UTC 2020

Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer.

Aging

Hao L,Pang K,Pang H,Zhang J,Zhang Z,He H,Zhou R,Shi Z,Han C

Tue Feb 04 00:00:00 UTC 2020

Cyclophilin B control of lysine post-translational modifications of skin type I collagen.

PLoS genetics

Terajima M,Taga Y,Cabral WA,Liu Y,Nagasawa M,Sumida N,Kayashima Y,Chandrasekaran P,Han L,Maeda N,Perdivara I,Hattori S,Marini JC,Yamauchi M

Sat Jun 01 00:00:00 UTC 2019

Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm.

AIMS genetics

Zimmerman SM,Besio R,Heard-Lipsmeyer ME,Dimori M,Castagnola P,Swain FL,Gaddy D,Diekman AB,Morello R

Wed Sep 30 00:00:00 UTC 2020

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

PLoS genetics

Heard ME,Besio R,Weis M,Rai J,Hudson DM,Dimori M,Zimmerman SM,Kamykowski JA,Hogue WR,Swain FL,Burdine MS,Mackintosh SG,Tackett AJ,Suva LJ,Eyre DR,Morello R

Fri Apr 01 00:00:00 UTC 2016

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

PLoS genetics

Heard ME,Besio R,Weis M,Rai J,Hudson DM,Dimori M,Zimmerman SM,Kamykowski JA,Hogue WR,Swain FL,Burdine MS,Mackintosh SG,Tackett AJ,Suva LJ,Eyre DR,Morello R

Fri Apr 01 00:00:00 UTC 2016

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

PLoS genetics

Heard ME,Besio R,Weis M,Rai J,Hudson DM,Dimori M,Zimmerman SM,Kamykowski JA,Hogue WR,Swain FL,Burdine MS,Mackintosh SG,Tackett AJ,Suva LJ,Eyre DR,Morello R

Fri Apr 01 00:00:00 UTC 2016

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

PLoS genetics

Heard ME,Besio R,Weis M,Rai J,Hudson DM,Dimori M,Zimmerman SM,Kamykowski JA,Hogue WR,Swain FL,Burdine MS,Mackintosh SG,Tackett AJ,Suva LJ,Eyre DR,Morello R

Fri Apr 01 00:00:00 UTC 2016

Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Gruenwald K,Castagnola P,Besio R,Dimori M,Chen Y,Akel NS,Swain FL,Skinner RA,Eyre DR,Gaddy D,Suva LJ,Morello R

Sat Mar 01 00:00:00 UTC 2014

Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Gruenwald K,Castagnola P,Besio R,Dimori M,Chen Y,Akel NS,Swain FL,Skinner RA,Eyre DR,Gaddy D,Suva LJ,Morello R

Sat Mar 01 00:00:00 UTC 2014

Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Gruenwald K,Castagnola P,Besio R,Dimori M,Chen Y,Akel NS,Swain FL,Skinner RA,Eyre DR,Gaddy D,Suva LJ,Morello R

Sat Mar 01 00:00:00 UTC 2014

Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Gruenwald K,Castagnola P,Besio R,Dimori M,Chen Y,Akel NS,Swain FL,Skinner RA,Eyre DR,Gaddy D,Suva LJ,Morello R

Sat Mar 01 00:00:00 UTC 2014

Bioinformatics

Protein Aliases: Endoplasmic reticulum protein SC65; leprecan-like 4; Leprecan-like protein 4; nucleolar autoantigen (55kD); Nucleolar autoantigen No55; nucleolar autoantigen, 55kDa; Prolyl 3-hydroxylase family member 4; SC65 synaptonemal complex protein; SC65 synaptonemal complex protein (Sc65-pending); Synaptonemal complex protein SC65

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Gene Aliases: 1110036O03Rik; AI413214; LEPREL4; NO55; NOL55; P3H4; SC65

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UniProt ID: (Human) Q92791, (Rat) Q64375, (Mouse) Q8K2B0

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Entrez Gene ID: (Human) 10609, (Rat) 59101, (Mouse) 66180

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Function(s)

molecular_function

Process(es)

synaptonemal complex assembly biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SC65 Polyclonal Antibody

SC65 Antibody (15288-1-AP) in WB

Product Details

15288-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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