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Proteintech
SCAMP2 Polyclonal Antibody
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Product Details
15119-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SCAMP2 Fusion Protein Ag7190 (1-152 aa encoded by BC001376)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSAFDTNPF ADPVDVNPFQ DPSVTQLTNA PQGGLAEFNP FSETNAATTV PVTQLPGSSQ PAVLQPSVEP TQPTPQAVVS AAQAGLLRQQ EELDRKAAEL ERKERELQNT VANLHVRQNN WPPLPSWCPV KPCFYQDFST EIPADYQRIC KML (1-152 aa encoded by BC001376)
Target Information
Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: scamp 2; Secretory carrier membrane protein 2; Secretory carrier-associated membrane protein 2; testis secretory sperm-binding protein Li 219p
Gene Aliases: AI875466; Sc2; SCAMP2
UniProt ID: (Human) O15127, (Mouse) Q9ERN0
Entrez Gene ID: (Human) 10066, (Rat) 65168, (Mouse) 24044
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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