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Invitrogen
SCAMP5 Monoclonal Antibody (K06322_12G11)
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FIGURE: 1 / 3
SCAMP5 Antibody (MA5-55689) in IHC (P)
Immunohistochemistry analysis of SCAMP5 in paraffin-embedded cerebellum tissue. Sample was incubated with SCAMP5 monoclonal antibody (Product # MA5-55689) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temperatu... View More
Product Details
MA5-55689
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
K06322_12G11
Immunogen
Human SCAMP5 peptide (immunogen range is 11-30).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_3667921
Product Specific Information
Sequence of this protein is as follows: LPKFIPLKPC FYQDFEADIP
Target Information
Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSCAMP5; Secretory carrier membrane protein 5; Secretory carrier-associated membrane protein 5
Gene Aliases: Sc5; SCAMP5
UniProt ID: (Human) Q8TAC9, (Mouse) Q9JKD3
Entrez Gene ID: (Human) 192683, (Mouse) 56807
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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