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Immunogen sequence: PNSAPKAGLP GATGPMAVRP EEAVRGLGAG TESSRRAQEP VSGCGSPEQD PQKQAEEERQ EEPEYENVVP I
The protein encoded by this gene is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acetyl LDL receptor; MGC47738; Scavenger receptor class F member 1; scavenger receptor class F, member 1; Scavenger receptor expressed by endothelial cells 1; SREC-I
Gene Aliases: KIAA0149; SCARF1; SREC; SREC-I; SREC1
UniProt ID: (Human) Q14162
Entrez Gene ID: (Human) 8578
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