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Invitrogen
SCN3B Polyclonal Antibody
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Product Details
PA5-28043
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SCN3B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545519
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2.
Predicted reactivity: Mouse (99%), Rat (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sodium channel regulatory subunit beta-3; sodium channel, voltage gated, type III beta subunit; sodium channel, voltage-gated, type III, beta subunit; voltage-gated sodium channel beta-3 subunit
Gene Aliases: ATFB16; BRGDA7; HSA243396; KIAA1158; SCN3B; SCNB3
UniProt ID: (Human) Q17RL3
Entrez Gene ID: (Human) 55800
sodium ion transport
nervous system development
positive regulation of heart rate
positive regulation of sodium ion transport
sensory perception of pain
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of postsynaptic membrane potential
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell action potential
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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