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Invitrogen
SCN3B Polyclonal Antibody
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Product Details
PA5-87803
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-160 of human SCN3B (NP_0608701)
Conjugate
Form
Liquid
Concentration
1.15 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804421
Product Specific Information
Immunogen sequence: FPVCVEVPSE TEAVQGNPMK LRCISCMKRE EVEATTVVEW FYRPEGGKDF LIYEYRNGHQ EVESPFQGRL QWNGSKDLQD VSITVLNVTL NDSGLYTCNV SREFEFEAHR PFVKTTRLIP LRVTEEAGED FTSVVSEI; Positive Samples: U-87MG, A-549, B-cell, Mouse lung, Mouse liver; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: sodium channel beta 3 subunit; Sodium channel regulatory subunit beta-3; sodium channel subunit beta-3
Gene Aliases: Scn3b; Scnb3
UniProt ID: (Rat) Q9JK00
Entrez Gene ID: (Rat) 245956
sodium ion transport
nervous system development
positive regulation of heart rate
positive regulation of sodium ion transport
sensory perception of pain
regulation of ion transmembrane transport
sodium ion transmembrane transport
membrane depolarization
cardiac muscle contraction
regulation of atrial cardiac muscle cell membrane depolarization
regulation of ventricular cardiac muscle cell membrane depolarization
cardiac conduction
protein localization to plasma membrane
cardiac muscle cell action potential involved in contraction
ventricular cardiac muscle cell action potential
membrane depolarization during action potential
membrane depolarization during cardiac muscle cell action potential
atrial cardiac muscle cell action potential
SA node cell to atrial cardiac muscle cell communication
regulation of heart rate by cardiac conduction
regulation of sodium ion transmembrane transporter activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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