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Product Details
PA5-27355
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human SCP3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2544831
Product Specific Information
Recommended positive controls: mouse testis.
Predicted reactivity: Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SCP-3; Synaptonemal complex protein 3
Gene Aliases: COR1; RPRGL4; SCP3; SPGF4; SYCP3
UniProt ID: (Human) Q8IZU3, (Mouse) P70281
Entrez Gene ID: (Human) 50511, (Mouse) 20962
male meiosis I
spermatogenesis, exchange of chromosomal proteins
cell division
meiotic DNA repair synthesis
cell cycle
female meiosis sister chromatid cohesion
mitotic nuclear division
meiotic nuclear division
synapsis
synaptonemal complex assembly
spermatogenesis
spermatid development
female meiosis chromosome segregation
sperm chromatin condensation
negative regulation of apoptotic process
chiasma assembly
female meiosis chromosome separation
meiotic cell cycle
lateral element assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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