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Immunogen sequence: MVFSYHNSF LIADRNEAWI LETAGKYWAA EKVQEGVRNI SNQLSITTKI AREHPDMRNY AKRKGWWDGK KEFDFAAAYS YLDTAKMMTS SGRYCEGYKL LNKHKGNITF ETMMEILRDK PSGINMEGEF LTTASMVSIL PQDSSLPCIH FFTGTPDPER SVFKPFIFVP HISQLLDTSS PTFELEDLVK KKSHFKPDRR HPLYQKHQQA LEVVNNNEEK AKIMLDNMRK LEKELFREME SILQNKHLDV EKIVNLFPQC TKDEIQIYQS NLSVKVSS (1-277 aa encoded by BC031821)
SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
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Protein Aliases: Secernin-3
Gene Aliases: 4833415E20Rik; AI427019; AV002033; SCRN3; SES3
UniProt ID: (Human) Q0VDG4, (Mouse) Q3TMH2
Entrez Gene ID: (Human) 79634, (Mouse) 74616, (Rat) 311731
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