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Product Details
PA5-53267
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SCYL1. Recombinant protein control fragment (Product #RP-91451).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2647042
Product Specific Information
Immunogen sequence: AFPEDFCRHK VLPQLLTAFE FGNAGAVVLT PLFKVGKFLS AEEYQQKIIP VVVKMFSSTD RAMRIRLLQQ MEQFIQYLDE PTVNTQIFPH VVHGFLDTNP AIREQTVKSM LLLAPKLNEA NLNVELMK
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Target Information
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coated vesicle-associated kinase of 90 kDa; likely ortholog of mouse N-terminal kinase-like protein; N-terminal kinase-like protein; SCY1-like protein 1; SCY1-like, kinase-like 1; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; telomerase transcriptional elements-interacting factor; Teratoma-associated tyrosine kinase
Gene Aliases: CVAK90; GKLP; HT019; NKTL; NTKL; P105; SCAR21; SCYL1; TAPK; TEIF; TRAP
UniProt ID: (Human) Q96KG9
Entrez Gene ID: (Human) 57410
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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