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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 105 kDa kinase-like protein; Coated vesicle-associated kinase of 90 kDa; likely ortholog of mouse N-terminal kinase-like protein; Mitosis-associated kinase-like protein NTKL; N-terminal kinase-like protein; SCY1-like 1 splice variant 13; SCY1-like 1 splice variant 15; SCY1-like protein 1; SCY1-like, kinase-like 1; Telomerase regulation-associated protein; Telomerase transcriptional element-interacting factor; telomerase transcriptional elements-interacting factor; Teratoma-associated tyrosine kinase; ubiquitous protein kinase-like (105 kDa)
Gene Aliases: 2810011O19Rik; C85140; CVAK90; GKLP; HT019; mdf; mfd; NKTL; NTKL; P105; SCAR21; SCYL1; TAPK; TEIF; TRAP
UniProt ID: (Human) Q96KG9, (Mouse) Q9EQC5, (Rat) Q5M9F8
Entrez Gene ID: (Human) 57410, (Mouse) 78891, (Rat) 293684
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