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Proteintech
SDCCAG8 Monoclonal Antibody (2H1A4)
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Product Details
66284-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2H1A4
Immunogen
SDCCAG8 Fusion Protein Ag4264 (1-360 aa encoded by BC032454)
Conjugate
Form
Liquid
Concentration
1.91 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAKSPENST LEEILGQYQR SLREHASRSI HQLTCALKEG DVTIGEDAPN LSFSTSVGNE DARTAWPELQ QSHAVNQLKD LLRQQADKES EVSPSRRRKM SPLRSLEHEE TNMPTMHDLV HTINDQSQYI HHLEAEVKFC KEELSGMKNK IQVVVLENEG LQQQLKSQRQ EETLREQTLL DASGNMHNSW ITTGEDSGVG ETSKRPFSHD NADFGKAASA GEQLELEKLK LTYEEKCEIE ESQLKFLRND LAEYQRTCED LKEQLKHKEF LLAANTCNRV GGLCLKCAQH EAVLSQTHTN VHMQTIERLV KERDDLMSAL VSVRSSLADT QQREASAYEQ VKQVLQISEE ANFEKTKHPS Q (1-360 aa encoded by BC032454)
Target Information
SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antigen NY-CO-8; Centrosomal colon cancer autoantigen protein; hCCCAP; Serologically defined colon cancer antigen 8
Gene Aliases: BBS16; CCCAP; CCCAP SLSN7; hCCCAP; HSPC085; NPHP10; NY-CO-8; SDCCAG8; SLSN7
UniProt ID: (Human) Q86SQ7
Entrez Gene ID: (Human) 10806
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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