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Invitrogen
SDHC Polyclonal Antibody
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Product Details
PA5-79966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human SDHC (35-50aa KEEMERFWNKNIGSNR).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2747081
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, Mouse Liver Tissue, HELA whole cell. IHC: Rat Gaster Tissue, Human Gastric Cancer Tissue.
Target Information
This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. There are several related pseudogenes for this gene on different chromosomes. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CYBL; cytochrome B large subunit of complex II; Integral membrane protein CII-3; integral membrane protein CII-3b; large subunit of cytochrome b; Malate dehydrogenase [quinone] cytochrome b560 subunit; QPs-1; QPs1; succinate dehydrgenase cytochrome b; succinate dehydrogenase 3, integral membrane subunit; Succinate dehydrogenase complex subunit C; succinate dehydrogenase complex subunit C integral membrane protein 15kDa; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Succinate-ubiquinone oxidoreductase cytochrome B large subunit
Gene Aliases: 0610010E03Rik; AI316496; AU019277; CYB560; CYBL; PGL3; QPS1; SDH3; SDHC
UniProt ID: (Human) Q99643, (Mouse) Q9CZB0
Entrez Gene ID: (Human) 6391, (Rat) 289217, (Mouse) 66052
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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