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Product Details
PA5-120093
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 37-145 of human SEC11A (NP_055115.1).
Conjugate
Form
Liquid
Concentration
1.08 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913665
Product Specific Information
Positive test controls include: SGC-7901, HT-29, Raji, HepG2, A-549, Mouse kidney, Mouse liver, Mouse lung, Rat brain. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass type II membrane protein.
Immunogen sequence: KGLMVITGSE SPIVVVLSGS MEPAFHRGDL LFLTNRVEDP IRVGEIVVFR IEGREIPIVH RVLKIHEKQN GHIKFLTKGD NNAVDDRGLY KQGQHWLEKK DVVGRARGF
Target Information
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SEC11 homolog A; Sec11-like 1; SEC11-like protein 1; Sid 2895; signal peptidase complex (18kD); signal peptidase complex 18; signal peptidase complex 18kD; Signal peptidase complex catalytic subunit SEC11A; SPase 18 kDa subunit; SPC18
Gene Aliases: 1810012E07Rik; 18kDa; SEC11A; SEC11L1; Sid2895; Sid2895p; SPC18; SPCS4A
UniProt ID: (Human) P67812, (Mouse) Q9R0P6
Entrez Gene ID: (Human) 23478, (Mouse) 56529, (Rat) 65166
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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