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FIGURE: 1 / 1
SEC23A Antibody (PA5-88348) in WB
Western blot analysis of SEC23A in extracts of various cell lines. Samples were incubated with SEC23A Polyclonal antibody (Product # PA5-88348) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-88348
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human Sec23A (NP_0063552)
Conjugate
Form
Liquid
Concentration
0.85 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804847
Product Specific Information
Immunogen sequence: MTTYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQFPPSYAG ISELNQPAEL LPQFSSIEYV VLRGPQMPLI FLYVVDTCME DEDLQALKES; Positive Samples: B-cell, LO2, HeLa, SGC-7901, HT-29, Mouse brain, Mouse liver, Rat brain; Cellular Location: Golgi apparatus membrane, Peripheral membrane protein, Smooth endoplasmic reticulum membrane
Target Information
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSec23A; MGC26267; Protein transport protein Sec23A; Sec23 homolog A, COPII coat complex component; SEC23-related protein A; SEC23A
Gene Aliases: CLSD; Msec23; Sec23; SEC23A; Sec23r
UniProt ID: (Human) Q15436, (Mouse) Q01405
Entrez Gene ID: (Human) 10484, (Mouse) 20334, (Rat) 58817
transport
intracellular protein transport
ER to Golgi vesicle-mediated transport
protein transport
vesicle-mediated transport
antigen processing and presentation of peptide antigen via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class II
COPII vesicle coating
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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