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Product Details
PA5-97205
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human SEC31A (NP_0557482)
Conjugate
Form
Liquid
Concentration
2.87 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809007
Product Specific Information
Immunogen sequence: PTNTQWCFDI QWCPRNPAVL SAASFDGRIS VYSIMGGSTD GLRQKQVDKL SSSFGNLDPF GTGQPLPPLQ IPQQTAQHSI VLPLKKPPKW IRRPVGASFS FGGKLVTFEN VRMPSHQGAE QQQQQHHVFI SQVVTEKEFL SRSDQLQQAV QSQGFINYCQ KKIDASQTEF EKNVWSFLKV NFEDDSRGKY LELLGYRKED L; Positive Samples: Mouse liver, Rat liver; Cellular Location: COPII-coated vesicle membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Peripheral membrane protein
Target Information
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABP125; ABP130; Protein transport protein Sec31A; SEC31 homolog A, COPII coating complex component; SEC31-like 1; SEC31-like protein 1; SEC31-related protein A; vesicle associated protein; Vesicle-associated protein 1; Web1-like protein; yeast Sec31p homolog
Gene Aliases: 1810024J13Rik; ABP125; ABP130; AU042160; HSPC275; HSPC334; KIAA0905; SEC31A; SEC31L1; VAP1
UniProt ID: (Human) O94979, (Mouse) Q3UPL0, (Rat) Q9Z2Q1
Entrez Gene ID: (Human) 22872, (Mouse) 69162, (Rat) 93646
transport
protein transport
vesicle-mediated transport
response to calcium ion
antigen processing and presentation of peptide antigen via MHC class I
ER to Golgi vesicle-mediated transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
IRE1-mediated unfolded protein response
COPII vesicle coating
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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