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Proteintech
SEC5/EXOC2 Monoclonal Antibody (1C11G2)
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Product Details
66011-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1C11G2
Immunogen
SEC5/EXOC2 Fusion Protein Ag17866 (456-806 aa encoded by BC016918)
Conjugate
Form
Liquid
Concentration
1.22 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TIQDLILDL RVRCVMATLQ HTAEEIKRLA EKEDWIVDNE GLTSLPCQFE QCIVCSLQSL KGVLECKPGE ASVFQQPKTQ EEVCQLSINI MQVFIYCLEQ LSTKPDADID TTHLSVDVSS PDLFGSIHED FSLTSEQRLL IVLSNCCYLE RHTFLNIAEH FEKHNFQGIE KITQVSMASL KELDQRLFEN YIELKADPIV GSLEPGIYAG YFDWKDCLPP TGVRNYLKEA LVNIIAVHAE VFTISKELVP RVLSKVIEAV SEELSRLMQC VSSFSKNGAL QARLEICALR DTVAVYLTPE SKSSFKQALE ALPQLSSGAD KKLLEELLNK FKSSMHLQLT CFQAASSTMM KT (456-806 aa encoded by BC016918)
Target Information
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Exocyst complex component 2; Exocyst complex component Sec5; rSec5; SEC5 homolog; SEC5-like 1
Gene Aliases: 2410030I24Rik; AI648199; EXOC2; Rsec5; SEC5; SEC5L1; Sec5p
UniProt ID: (Human) Q96KP1, (Mouse) Q9D4H1, (Rat) O54921
Entrez Gene ID: (Human) 55770, (Mouse) 66482, (Rat) 171455
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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