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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SEC61B Antibodies

          Proteintech

          SEC61B Polyclonal Antibody

          1 Reference
          View all (6) SEC61B antibodies

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          Cite SEC61B Polyclonal Antibody

          • Antibody Testing Data (11)
          SEC61B Antibody in Immunocytochemistry (ICC/IF)
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          SEC61B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 11

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          SEC61B Antibody (14846-1-AP) in ICC/IF

          Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 14846-1-AP (SEC61B-Specific antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SEC61B Antibody in Immunocytochemistry (ICC/IF)
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEC61B Antibody in Western Blot (WB)
          SEC61B Antibody in Western Blot (WB)
          SEC61B Antibody in Western Blot (WB)
          SEC61B Antibody in Western Blot (WB)

          Product Details

          14846-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.19 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: protein translocation complex beta; protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; sec61 beta; Sec61 beta subunit; Sec61 complex, beta subunit

          View more View less

          Gene Aliases: 1190006C12Rik; AI326121; AW122942; SEC61B

          View more View less

          UniProt ID: (Human) P60468, (Mouse) Q9CQS8

          View more View less

          Entrez Gene ID: (Human) 10952, (Mouse) 66212, (Rat) 298068

          View more View less

          Function(s)
          protein binding poly(A) RNA binding epidermal growth factor binding ribosome binding molecular_function
          Process(es)
          protein import into nucleus, translocation transport intracellular protein transport protein transport ER-associated ubiquitin-dependent protein catabolic process retrograde protein transport, ER to cytosol biological_process IRE1-mediated unfolded protein response
          It has to be done as per old AB suggested Products section.
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