Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
SEC62 Antibody (MA5-50796) in WB
Western blot analysis of SEC62 in different various lysates. Lane 1: NIH/3T3 cell lysate (20 µg/Lane); Lane 2: PC-12 cell lysate (20 µg/Lane); Lane 3: Mouse liver tissue lysate (40 µg/Lane); Lane 4: Rat liver tissue lysate (40 µg/Lane); Lane 5: Human liver tissue lysate (40 µg/Lane); Lane 6: Mouse brain tissue lysate (40 µg/Lane). Predicted band size: 46 kDa. Observed band size: 56 kDa. Exposure time: 2 minutes; 10% SDS-PAGE gel. Primary antibody SEC62 recombinant monoclonal antibody (Product # MA5-50796) with a dilution of 1:5,000 was use... View More
Product Details
MA5-50796
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH0-25
Immunogen
Synthetic peptide within human SEC62 aa 1-50/399.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093906
Product Specific Information
Positive control: Hela cell lysate, K562 cell lysate, SH-SY5Y cell lysate, HepG2 cell lysate, 293T cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, human liver tissue lysate, mouse brain tissue lysate.
Predicted band size: 46 kDa
Subcellular Location: Endoplasmic reticulum membrane.
Target Information
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: hTP-1; membrane protein SEC62, S.cerevisiae, homolog of; SEC62 homolog; SEC62 preprotein translocation factor; TP-1; Translocation protein 1; Translocation protein SEC62
Gene Aliases: 3100002M17Rik; Ab2-292; AI844545; AW545092; Dtrp1; HTP1; SEC62; TLOC1; TP-1
UniProt ID: (Human) Q99442, (Mouse) Q8BU14
Entrez Gene ID: (Human) 7095, (Mouse) 69276, (Rat) 294912
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support