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Invitrogen
SEMA5A Polyclonal Antibody
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Product Details
PA5-116598
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 330-500 of human SEMA5A (NP_0039572)
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901229
Product Specific Information
Positive Samples: Mouse liver
Immunogen sequence: AFSGPFKYQE NSRSAWLPYP NPNPHFQCGT VDQGLYVNLT ERNLQDAQKF ILMHEVVQPV TTVPSFMEDN SRFSHVAVDV VQGREALVHI IYLATDYGTI KKVRVPLNQT SSSCLLEEIE LFPERRREPI RSLQILHSQS VLFVGLREHV VKIPLKRCQF YRTRSTCIGA Q
Target Information
Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996 [PubMed 8817451]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: M-Sema D; sema F; semaphorin F; semaphorin-5A; semaphorin-F
Gene Aliases: 5930434A13; 9130201M22Rik; AI464145; Semaf; semF
Entrez Gene ID: (Mouse) 20356
patterning of blood vessels
positive regulation of endothelial cell proliferation
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
negative regulation of cell adhesion
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
diencephalon development
cell differentiation
positive regulation of actin filament depolymerization
positive regulation of catenin import into nucleus
positive regulation of angiogenesis
branching morphogenesis of an epithelial tube
positive regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
positive chemotaxis
positive regulation of protein kinase B signaling
cell chemotaxis
semaphorin-plexin signaling pathway
positive regulation of extracellular matrix disassembly
signal clustering
negative regulation of endothelial cell apoptotic process
positive regulation of endothelial cell chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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