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Invitrogen
SEMA5A Monoclonal Antibody (C3)
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SEMA5A Antibody (MA5-51131) in WB
Western blot analysis of SEMA5A in Rat Cerebrum lysate. Samples were incubated with SEMA5A monoclonal antibody (Product # MA5-51131) using a dilution of 0.2 µg/mL followed by HRP-Linked Caprine Anti-Mouse IgG secondary antibody at a dilution of 0.2 µg/mL.
Product Details
MA5-51131
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C3
Immunogen
Recombinant Human SEMA5A protein, Val319-Gln668 (Accession #Q13591)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3093371
Target Information
Members of the semaphorin protein family, such as SEMA5A, are involved in axonal guidance during neural development (Adams et al., 1996 [PubMed 8817451]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A; Sema F; sema5a {ECO:0000312|Ensembl:ENSRNOP00000016506}; semaphorin 5A; semaphorin F; Semaphorin-5A; semaphorin-5A {ECO:0000250|UniProtKB:Q13591}; Semaphorin-F
Gene Aliases: SEMA5A; SEMAF; semF
UniProt ID: (Human) Q13591, (Rat) D3ZTD8
Entrez Gene ID: (Human) 9037, (Rat) 310207
neural crest cell migration
positive regulation of endothelial cell proliferation
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
cell adhesion
negative regulation of cell adhesion
cell-cell signaling
nervous system development
axonal fasciculation
diencephalon development
positive regulation of cell migration
positive regulation of actin filament depolymerization
positive regulation of catenin import into nucleus
positive regulation of angiogenesis
positive regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
positive chemotaxis
negative chemotaxis
positive regulation of protein kinase B signaling
cell chemotaxis
semaphorin-plexin signaling pathway
signal clustering
negative regulation of endothelial cell apoptotic process
positive regulation of endothelial cell chemotaxis
patterning of blood vessels
axon guidance
branching morphogenesis of an epithelial tube
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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