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Product Details
19529-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody is specific to SENP5.
Target Information
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the "GG" region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp564O1016; FLJ42398; MGC27076; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5; Smt3ip3; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5
Gene Aliases: 6230429P13Rik; A730063F07Rik; AI851888; BB189556; FKSG45; SENP5; SMT3IP3
UniProt ID: (Human) Q96HI0, (Mouse) Q6NXL6
Entrez Gene ID: (Human) 205564, (Mouse) 320213, (Rat) 303874
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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