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          • Primary Antibodies ›
          • SENP5 Antibodies

          Invitrogen

          SENP5 Polyclonal Antibody

          View all (7) SENP5 antibodies

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          Cite SENP5 Polyclonal Antibody

          • Antibody Testing Data (2)
          SENP5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SENP5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SENP5 Antibody (PA5-75185) in IHC (P)

          Immunohistochemistry analysis of SENP5 in paraffin-embedded human lung carcinoma tissue. Samples were incubated with SENP5 polyclonal antibody (Product # PA5-75185) at a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SENP5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SENP5 Antibody in Western Blot (WB)

          Product Details

          PA5-75185

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids 650-697 of Human SENP5.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2718913

          Product Specific Information

          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

          Target Information

          SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the "GG" region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: DKFZp564O1016; FLJ42398; MGC27076; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5; Smt3ip3; SUMO/sentrin specific protease 5; SUMO/Smt3-specific isopeptidase 3; SUMO1/sentrin specific peptidase 5; SUMO1/sentrin specific protease 5; Sumo1/sentrin/SMT3 specific peptidase 5

          View more View less

          Gene Aliases: 6230429P13Rik; A730063F07Rik; AI851888; BB189556; FKSG45; SENP5; SMT3IP3

          View more View less

          UniProt ID: (Human) Q96HI0, (Mouse) Q6NXL6

          View more View less

          Entrez Gene ID: (Human) 205564, (Mouse) 320213, (Rat) 303874

          View more View less

          Function(s)
          endopeptidase activity protein binding SUMO-specific protease activity SUMO-specific endopeptidase activity molecular_function peptidase activity cysteine-type peptidase activity hydrolase activity
          Process(es)
          proteolysis cell cycle biological_process cell division protein sumoylation protein desumoylation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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