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Abnova
SENP5 Monoclonal Antibody (3C2)
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Product Details
H00205564-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
3C2
Immunogen
SENP5 (NP_689912, 2 a.a. approximately 109 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: KKQRKILWRK GIHLAFSEKW NTGFGGFKKF YFHQHLCILK AKLGRPVTWN RQLRHFQGRK KALQIQKTWI KDEHLCAKTK FNVATQNVST LSSKVKRKDA KHFISSSK
Target Information
SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the "GG" region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564O1016; FLJ42398; MGC27076; Sentrin-specific protease 5; Sentrin/SUMO-specific protease SENP5; SUMO1/sentrin specific protease 5
Gene Aliases: FKSG45; SENP5
UniProt ID: (Human) Q96HI0
Entrez Gene ID: (Human) 205564
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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