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Immunogen sequence: KLLAGLTRPD VRPPLGRGLV GGQEEASQEA GLPAGAGPSP TFPALGI
This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. This protein itself contains a selenocysteine residue in its predicted active site. The 3' UTR of the gene has a stem-loop secondary structure called a selenocysteine insertion sequence (SECIS) element, which allows UGA to direct the incorporation of selenocysteine rather than signal a translational stop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: selenide; Selenide, water dikinase 2; Selenium donor protein 2; Selenophosphate synthase 2
Gene Aliases: SEPHS2; SPS2; SPS2b
UniProt ID: (Human) Q99611
Entrez Gene ID: (Human) 22928
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