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          • Primary Antibodies ›
          • SEPP1 Antibodies

          Invitrogen

          SEPP1 Polyclonal Antibody

          View all (5) SEPP1 antibodies

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          Datasheet
          Protocols
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          Datasheet
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          Cite SEPP1 Polyclonal Antibody

          • Antibody Testing Data (3)
          SEPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          SEPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          SEPP1 Antibody (PA5-103044) in IHC (P)

          Immunohistochemistry analysis of SEPP1 in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with SEPP1 polyclonal antibody (Product # PA5-103044) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SEPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEPP1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SEPP1 Antibody in Western Blot (WB)

          Product Details

          PA5-103044

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:3,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Non-human primate, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human SELENOP(Accession P49908), corresponding to amino acid residues A239-R261.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          RRID

          AB_2852414

          Product Specific Information

          Antibody detects endogenous levels of total SEPP1.

          Target Information

          A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in anti-oxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. Selenoprotein M (SelM) is especially expressed in a mammalian brain and is localized to the perinuclear structures (Golgi/ER). The roles of selM have not been clearly identified until present time.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Selenoprotein P; SeP

          View more View less

          Gene Aliases: SELENOP; SELP; SeP; SEPP; SEPP1

          View more View less

          UniProt ID: (Human) P49908, (Rat) P25236

          View more View less

          Entrez Gene ID: (Human) 6414, (Rat) 29360

          View more View less

          Function(s)
          selenium binding
          Process(es)
          selenium compound metabolic process platelet degranulation response to oxidative stress brain development locomotory behavior post-embryonic development sexual reproduction growth response to selenium ion
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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