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Product Details
13619-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SERCA3 Fusion Protein Ag4527 (323-999 aa encoded by BC035729)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TRRMARKNA IVRSLPSVET LGCTSVICSD KTGTLTTNQM SVCRMFVVAE ADAGSCLLHE FTISGTTYTP EGEVRQGDQP VRCGQFDGLV ELATICALCN DSALDYNEAK GVYEKVGEAT ETALTCLVEK MNVFDTDLQA LSRVERAGAC NTVIKQLMRK EFTLEFSRDR KSMSVYCTPT RPHPTGQGSK MFVKGAPESV IERCSSVRVG SRTAPLTPTS REQILAKIRD WGSGSDTLRC LALATRDAPP RKEDMELDDC SKFVQYETDL TFVGCVGMLD PPRPEVAACI TRCYQAGIRV VMITGDNKGT AVAICRRLGI FGDTEDVAGK AYTGREFDDL SPEQQRQACR TARCFARVEP AHKSRIVENL QSFNEITAMT GDGVNDAPAL KKAEIGIAMG SGTAVAKSAA EMVLSDDNFA SIVAAVEEGR AIYSNMKQFI RYLISSNVGE VVCIFLTAIL GLPEALIPVQ LLWVNLVTDG LPATALGFNP PDLDIMEKLP RSPREALISG WLFFRYLAIG VYVGLATVAA ATWWFVYDAE GPHINFYQLR NFLKCSEDNP LFAGIDCEVF ESRFPTTMAL SVLVTIEMCN ALNSVSENQS LLRMPPWMNP WLLVAVAMSM ALHFLILLVP PLPLIFQVTP LSGRQWVVVL QISLPVILLD EALKYLSRNH MHEEMSQK (323-999 aa encoded by BC035729)
Target Information
ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium ATPases (SERCA). The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. SERCA3 has been found to co-express with SERCA2b in platelets, mast cells, lymphoid cells, and epithelial cells. Due to this pattern of expression it is referred to as the non-muscle form of SERCA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adenosine triphosphatase, calcium; ATPase, Ca(2+)-transporting, ubiquitous; ATPase, Ca++ transporting, ubiquitous; Calcium pump 3; calcium-translocating P-type ATPase; sarco/endoplasmic reticulum Ca2+ -ATPase; sarcoendoplasmic reticulum Ca2+ ATPase type 3; Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; SERCA3; SR Ca(2+)-ATPase 3
Gene Aliases: ATP2A3; SERCA3; SERCA3b
UniProt ID: (Human) Q93084, (Rat) P18596, (Mouse) Q64518
Entrez Gene ID: (Human) 489, (Rat) 25391, (Mouse) 53313
Performance Guarantee
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