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SERF2 Antibody (PA5-103311) in ICC/IF
Immunocytochemistry analysis of SERF2 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with SERF2 polyclonal antibody (Product # PA5-103311) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-103311
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SERF2(Accession P84101), corresponding to amino acid residues M1-L31.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852656
Product Specific Information
Antibody detects endogenous levels of total SERF2.
Target Information
SERF2 (small EDRK-rich factor 2) is the human ortholog of the C/ elegans MOAG-4 gene. Serf2 (small EDRK-rich factor 2) is the human ortholog of the C. elegans MOAG-4 gene. MOAG-4 was shown to be a positive regulator of protein aggregates. Inactivation of MOAG-4 leads to a rescue from proteotoxcity, and could play a role in human diseases such as Alzheimer's disease and Parkinson's disease. In addition, SERF2 can induce huntingtin aggregation in SK-N-SH neuroblastoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 4F5rel; 4F5rel (4F5 related); Gastric cancer-related protein VRG107; Protein 4F5-related; Small EDRK-rich factor 2
Gene Aliases: 4F5REL; C80083; FAM2C; H4F5REL; HsT17089; m4F5rel; Msmac1l; SERF2
UniProt ID: (Human) P84101, (Mouse) P84102
Entrez Gene ID: (Human) 10169, (Mouse) 378702
Performance Guarantee
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