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Predicted to react with Mouse samples.
SERF2 (small EDRK-rich factor 2) is the human ortholog of the C/ elegans MOAG-4 gene. Serf2 (small EDRK-rich factor 2) is the human ortholog of the C. elegans MOAG-4 gene. MOAG-4 was shown to be a positive regulator of protein aggregates. Inactivation of MOAG-4 leads to a rescue from proteotoxcity, and could play a role in human diseases such as Alzheimer's disease and Parkinson's disease. In addition, SERF2 can induce huntingtin aggregation in SK-N-SH neuroblastoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4F5rel; 4F5rel (4F5 related); Gastric cancer-related protein VRG107; Protein 4F5-related; Small EDRK-rich factor 2
Gene Aliases: 4F5REL; C80083; FAM2C; H4F5REL; HsT17089; m4F5rel; Msmac1l; SERF2
UniProt ID: (Human) P84101, (Mouse) P84102
Entrez Gene ID: (Human) 10169, (Mouse) 378702
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