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Product Details
H00005104-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SERPINA5 (AAH08915, 17 a.a. approximately 406 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: ASLHRHHPRE MKKRVEDLHV GATVAPSSRR DFTFDLYRAL ASAAPSQNIF FSPVSISMSL AMLSLGAGSS TKMQILEGLG LNLQKSSEKE LHRGFQQLLQ ELNQPRDGFQ LSLGNALFTD LVVDLQDTFV SAMKTLYLAD TFPTNFRDSA GAMKQINDYV AKQTKGKIVD LLKNLDSNAV VIMVNYIFFK AKWETSFNHK GTQEQDFYVT SETVVRVPMM SREDQYHYLL DRNLSCRVMG VPYQGNATAL FILPSEGKMQ QVENGLSEKT LRKWLKMFKK RQLELYLPKF SIEGSYQLEK VLPSLGISNV FTSHADLSGI SNHSNIQVSE MVHKAVVEVD ESGTRAAAAT GTIFTFRSAR LNSQRLVFNR PFLMFIVDNN ILFLGRVNRP
Target Information
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acrosomal serine protease inhibitor; antitr; PAI-3; PCI; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; plasminogen activator inhibitor III; plasminogen activator inhibitor-3; Protein C inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5; Serpin A5; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Gene Aliases: PAI-3; PAI3; PCI; PCI-B; PLANH3; PROCI; SERPINA5
UniProt ID: (Human) P05154
Entrez Gene ID: (Human) 5104
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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