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SERPINB13 Antibody (PA5-89404) in WB
Western blot analysis of SERPINB13 in extracts of various cell lines. Samples were incubated with SERPINB13 Polyclonal antibody (Product # PA5-89404) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89404
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human SERPINB13 (NP_0365291)
Conjugate
Form
Liquid
Concentration
1.40 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2805550
Product Specific Information
Immunogen sequence: MDSLGAVSTR LGFDLFKELK KTNDGNIFFS PVGILTAIGM VLLGTRGATA SQLEEVFHSE KETKSSRIKA EEKEVIENTE AVHQQFQKFL TEISKLTNDY ELNITNRLFG EKTYLFLQKY LDYVEKYYHA SLEPVDFVNA; Positive Samples: Mouse uterus, Rat uterus; Cellular Location: Cytoplasm
Target Information
Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with essential biological processes such as fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. However, a subset of the serpin superfamily, the ov-serpins, also resides intracellularly. Differential display was used to identify a novel serpin (headpin or SERPINB13) that is under expressed in squamous cell cancers of the oral cavity. SERPINB13 is expressed in normal oral mucosal tissue, skin, and cultured keratinocytes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HaCaT UV-repressible serpin; Headpin; HURPIN; Peptidase inhibitor 13; PI-13; protease inhibitor 13 (hurpin, headpin); Proteinase inhibitor 13; serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13; Serpin B13; serpin peptidase inhibitor, clade B (ovalbumin), member 13; UV-B repressed sequence, HUR 7
Gene Aliases: 5430417G24; headpin; HSHUR7SEQ; HUR7; HURPIN; PI13; SERPINB13
UniProt ID: (Human) Q9UIV8, (Mouse) Q8CDC0
Entrez Gene ID: (Human) 5275, (Rat) 304690, (Mouse) 241196
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