Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: EQFDRKYTRG MLFKTNEEKK TVQMMFKEAK FKMGYADEVH TQVLELPYVE EELSMVILLP DDNTDLAVKE
The superfamily of high molecular weight serine proteinase inhibitors. A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAP-2; Cytoplasmic antiproteinase 2; Peptidase inhibitor 8; PI-8; protease inhibitor 8 (ovalbumin type); serine (or cysteine) peptdiase inhibitor, clade B, member 8; serine (or cysteine) peptidase inhibitor, clade B, member 8; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; serine (or cysteine) proteinase inhibitor, clade B, member 8; serine protease inhibitor 8; Serpin B8; serpin peptidase inhibitor, clade B (ovalbumin), member 8
Gene Aliases: CAP-2; CAP2; NK10; ovalbumin; PI8; SERPINB8; Spi8
UniProt ID: (Human) P50452, (Mouse) O08800
Entrez Gene ID: (Human) 5271, (Rat) 288937, (Mouse) 20725
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