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Invitrogen
SERPINE2 Polyclonal Antibody
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SERPINE2 Antibody (PA5-89894) in WB
Western blot analysis of SERPINE2 in extracts of Mouse testis. Samples were incubated with SERPINE2 Polyclonal antibody (Product # PA5-89894) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-89894
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-398 of human SERPINE2 (NP_0062071)
Conjugate
Form
Liquid
Concentration
0.94 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805827
Product Specific Information
Immunogen sequence: LEELGSNTGI QVFNQIVKSR PHDNIVISPH GIASVLGMLQ LGADGRTKKQ LAMVMRYGVN GVGKILKKIN KAIVSKKNKD IVTVANAVFV KNASEIEVPF VTRNKDVFQC EVRNVNFEDP ASACDSINAW VKNETRDMID NLLSPDLIDG VLTRLVLVNA VYFKGLWKSR FQPENTKKRT FVAADGKSYQ VPMLAQLSVF RCGSTSAPND LWYNFIELPY HGESISMLIA LPTESSTPLS AIIPHISTKT IDSWMSIMVP KRVQVILPKF TAVAQTDLKE PLKVLGITDM FDSSKANFAK ITTGSENLHV SHILQKAKIE VSEDGTKASA ATTAILIARS SPPWFIVDRP FLFFIRHNPT GAVLFMGQIN KP; Positive Samples: Mouse testis; Cellular Location: extracellular space
Target Information
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; Glia-derived nexin/protease nexin I; P17; Peptidase inhibitor 7; PI-7; plasminogen activator inhibitor type 1; PN-1; Protease nexin 1; Protease nexin I; protease nexin PN-1; serine (or cysteine) peptidase inhibitor, clade E, member 2; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; serine (or cysteine) proteinase inhibitor, clade E, member 2; serine protease inhibitor 4; Serine protease-inhibitor 4; Serpin E2; serpin peptidase inhibitor, clade E, member 2; SERPINE 2
Gene Aliases: B230326M24Rik; Gdnpn1; PAI-1; PI-7; PI7; PN-1; Pn1; Serpine2; Spi4; Spin4
UniProt ID: (Rat) P07092, (Mouse) Q07235
Entrez Gene ID: (Rat) 29366, (Mouse) 20720
embryo implantation
blood coagulation
negative regulation of cell proliferation
response to radiation
response to wounding
negative regulation of peptidase activity
negative regulation of platelet activation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
negative regulation of blood coagulation
negative regulation of cell growth
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
multicellular organism development
nervous system development
negative regulation of protein processing
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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