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Abnova
SERPINE2 Monoclonal Antibody (3G12)
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Product Details
H00005270-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3G12
Immunogen
SERPINE2 (NP_006207, 72 a.a. approximately 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: RTKKQLAMVM RYGVNGVGKI LKKINKAIVS KKNKDIVTVA NAVFVKNASE IEVPFVTRNK DVFQCEVRNV NFEDPASACD SINAWVKNET RDMIDNLLSP D
Target Information
This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDN; Glia derived nexin; Glia-derived nexin; glial-derived neurite promoting factor; P17; Peptidase inhibitor 7; PI-7; PN-1; Protease nexin 1; Protease nexin I; Serpin E2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; SERPINE 2
Gene Aliases: GDN; GDNPF; PI-7; PI7; PN-1; PN1; PNI; SERPINE2
UniProt ID: (Human) P07093
Entrez Gene ID: (Human) 5270
embryo implantation
blood coagulation
negative regulation of cell proliferation
response to radiation
negative regulation of plasminogen activation
negative regulation of sodium ion transport
negative regulation of endopeptidase activity
negative regulation of protein processing
positive regulation of neuron projection development
negative regulation of phosphatidylinositol 3-kinase signaling
cerebellar granular layer morphogenesis
negative regulation of blood coagulation
negative regulation of cell growth
regulation of cell migration
secretion by cell
secretory granule organization
negative regulation of protein catabolic process
mating plug formation
negative regulation of proteolysis
negative regulation of smoothened signaling pathway
regulation of timing of cell differentiation
positive regulation of astrocyte differentiation
detection of mechanical stimulus involved in sensory perception
regulation of synaptic transmission, glutamatergic
long-term synaptic potentiation
innervation
seminal vesicle epithelium development
dense core granule biogenesis
negative regulation of platelet aggregation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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