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          • Primary Antibodies ›
          • SERPING1/SERPINC1 Antibodies

          Proteintech

          SERPING1/C1 Inactivator Polyclonal Antibody

          11 References
          View all (2) SERPING1/SERPINC1 antibodies

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          Cite SERPING1/C1 Inactivator Polyclonal Antibody

          • Antibody Testing Data (13)
          SERPING1/C1 Inactivator Antibody in Immunocytochemistry (ICC/IF)
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          SERPING1/C1 Inactivator Antibody in Immunocytochemistry (ICC/IF)
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          FIGURE: 1 / 13

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          SERPING1/C1 Inactivator Antibody (12259-1-AP) in ICC/IF

          Immunofluorescent analysis of HepG2 cells using 12259-1-AP (SERPING1/C1 Inactivator antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SERPING1/C1 Inactivator Antibody in Immunocytochemistry (ICC/IF)
          SERPING1/C1 Inactivator Antibody in Immunocytochemistry (ICC/IF)
          SERPING1/C1 Inactivator Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SERPING1/C1 Inactivator Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SERPING1/C1 Inactivator Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SERPING1/C1 Inactivator Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)
          SERPING1/C1 Inactivator Antibody in Western Blot (WB)

          Product Details

          12259-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 5 publications 5 publications

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human, Mouse

          Published species

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SERPING1/C1 Inactivator Fusion Protein Ag2819 (151-500 aa encoded by BC011171)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.19 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LKLYHAFSA MKKVETNMAF SPFSIASLLT QVLLGAGENT KTNLESILSY PKDFTCVHQA LKGFTTKGVT SVSQIFHSPD LAIRDTFVNA SRTLYSSSPR VLSNNSDANL ELINTWVAKN TNNKISRLLD SLPSDTRLVL LNAIYLSAKW KTTFDPKKTR MEPFHFKNSV IKVPMMNSKK YPVAHFIDQT LKAKVGQLQL SHNLSLVILV PQNLKHRLED MEQALSPSVF KAIMEKLEMS KFQPTLLTLP RIKVTTSQDM LSIMEKLEFF DFSYDLNLCG LTEDPDLQVS AMQHQTVLEL TETGVEAAAA SAISVARTLL VFEVQQPFLF MLWDQQHKFP VFMGRVYDPR A (151-500 aa encoded by BC011171)

          Target Information

          This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: anti-thrombin 3; antithrombin; Antithrombin-III; ATIII; C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; complement component 1 inhibitor; Plasma protease C1 inhibitor; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin C1; Serpin G1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

          View more View less

          Gene Aliases: AI114908; At-3; AT3; AT3D; ATIII; C1IN; C1INH; C1NH; HAE1; HAE2; PRO0309; SERPINC1; SERPING1; THPH7

          View more View less

          UniProt ID: (Human) P01008, (Human) P05155, (Mouse) P32261, (Mouse) P97290

          View more View less

          Entrez Gene ID: (Human) 462, (Human) 710, (Mouse) 11905, (Mouse) 12258

          View more View less

          Function(s)
          protease binding serine-type endopeptidase inhibitor activity protein binding heparin binding peptidase inhibitor activity complement binding
          Process(es)
          negative regulation of complement activation, lectin pathway platelet degranulation complement activation, classical pathway aging blood coagulation, intrinsic pathway blood circulation negative regulation of endopeptidase activity fibrinolysis innate immune response immune system process blood coagulation hemostasis negative regulation of peptidase activity regulation of blood coagulation negative regulation of complement activation response to nutrient negative regulation of inflammatory response regulation of blood coagulation, intrinsic pathway
          It has to be done as per old AB suggested Products section.
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