Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 85%; Dog: 86%; Goat: 100%; Guinea Pig: 100%; Horse: 79%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
The protein encoded by this gene is a member of the serine protease inhibitor superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Myoepithelium-derived serine protease inhibitor; Pancpin; Pancreas-specific protein TSA2004; Peptidase inhibitor 14; PI-14; protease inhibitor 14; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2; serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2; Serpin I2; serpin peptidase inhibitor, clade I (pancpin), member 2; SERPIN12
Gene Aliases: MEPI; PANCPIN; PI14; SERPINI2; TSA2004
UniProt ID: (Human) O75830
Entrez Gene ID: (Human) 5276
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