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Product Details
PA5-88240
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 56-405 of human SERPINI2 (NP_0062081)
Conjugate
Form
Liquid
Concentration
1.31 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804767
Product Specific Information
Immunogen sequence: LEMVQLGAKG KAQQQIRQTL KQQETSAGEE FFVLKSFFSA ISEKKQEFTF NLANALYLQE GFTVKEQYLH GNKEFFQSAI KLVDFQDAKA CAEMISTWVE RKTDGKIKDM FSGEEFGPLT RLVLVNAIYF KGDWKQKFRK EDTQLINFTK KNGSTVKIPM MKALLRTKYG YFSESSLNYQ VLELSYKGDE FSLIIILPAE GMDIEEVEKL ITAQQILKWL SEMQEEEVEI SLPRFKVEQK VDFKDVLYSL NITEIFSGGC DLSGITDSSE VYVSQVTQKV FFEINEDGSE AATSTGIHIP VIMSLAQSQF IANHPFLFIM KHNPTESILF MGRVTNPDTQ EIKGRDLDSL; Positive Samples: Mouse pancreas, Rat pancreas
Target Information
The protein encoded by this gene is a member of the serine protease inhibitor superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neuroserpin; pancreas-specific serpin; serine (or cysteine) peptidase inhibitor, clade I, member 2; Serine protease inhibitor 14; Serpin I2; serpin peptidase inhibitor, clade I, member 2; SERPIN12
Gene Aliases: Serpini2; Spi14
UniProt ID: (Mouse) Q9JK88
Entrez Gene ID: (Rat) 171149, (Mouse) 67931
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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