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Proteintech
SESN3 Polyclonal Antibody
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Product Details
24532-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SESN3 Fusion Protein Ag21380 (199-262 aa encoded by BC017296)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: HYHALASFV FGSGINPERD PEISNGFRLI SVNNFCVCDL ANDNNIENAS LSGSNFGIVD SLSEL (199-262 aa encoded by BC017296)
Target Information
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sestrin-3
Gene Aliases: SESN3; SEST3
UniProt ID: (Human) P58005
Entrez Gene ID: (Human) 143686
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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