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Abnova
SESN3 Monoclonal Antibody (2C9)
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Product Details
H00143686-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2C9
Immunogen
SESN3 (AAH17296, 212 a.a. approximately 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: INPERDPEIS NGFRLISVNN FCVCDLANDN NIENASLSGS NFGIVDSLSE LEALMERMKR LQEEREDEEA SQEEMSTRFE KEKKESLFVV SGDTFHSFPH SGAFLHFFAF
Target Information
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562). May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sestrin-3
Gene Aliases: SESN3; SEST3
UniProt ID: (Human) P58005
Entrez Gene ID: (Human) 143686
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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